Cytokine gene polymorphisms and sudden infant death syndrome.

  title={Cytokine gene polymorphisms and sudden infant death syndrome.},
  author={Linda Ferrante and Siri Hauge Opdal and Ashild Vege and T O Rognum},
  journal={Acta paediatrica},
  volume={99 3},
AIM Several studies indicate that the mucosal immune system is stimulated in cases of sudden infant death syndrome (SIDS), and our hypothesis is that this immune reaction is because of an unfavourable combination of functional polymorphisms in the cytokine genes. METHODS Thus, in this study, single nucleotide polymorphisms (SNPs) in the genes encoding IL-6, IL-8, IL-12, IL-13, IL-16, IL-18 and IFNgamma were investigated in 148 SIDS cases, 56 borderline SIDS cases, 41 cases of infectious death… CONTINUE READING