Cytokine gene polymorphisms: methods of detection and biological significance.


In recent years, several functional polymorphisms, particularly, SNPs have been identified in cytokines and their receptor genes that regulate levels of cytokine expression. These have been implicated as immune prognostic markers in diseases, including differential response to therapy and as biomarkers of graft outcome following organ and stem cell… (More)
DOI: 10.1007/978-1-61779-842-9_31


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