Cytokine gene expression in different strains of mice with endotoxin-induced uveitis (EIU).

@article{Shen2000CytokineGE,
  title={Cytokine gene expression in different strains of mice with endotoxin-induced uveitis (EIU).},
  author={Defen Shen and Ronald R Buggage and Heather Eng and Chi Chao Chan},
  journal={Ocular immunology and inflammation},
  year={2000},
  volume={8 4},
  pages={221-5}
}
PURPOSE The kinetics of various cytokines in the eye plays a critical role in endotoxin-induced uveitis (EIU). This study examined the cytokine kinetics and susceptibility of EIU in four mice strains. METHODS Four strains of TLR-4 or Toll-like receptor-4 (Lps, lipopolysaccharide-susceptible) gene-positive mice (C3H/HeN of H-2(k), C57/B6 of H-2(b), Balb/C of H-2(d), and 129/J of H-2(b)) were injected subcutaneously with either lipopolysaccharide (LPS) in phosphate-buffered saline (PBS) or PBS… CONTINUE READING
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