Cytokine expression in vivo during murine herpetic stromal keratitis. Effect of protective antibody therapy.

@article{Staats1993CytokineEI,
  title={Cytokine expression in vivo during murine herpetic stromal keratitis. Effect of protective antibody therapy.},
  author={Herman F Staats and Robert N. Lausch},
  journal={Journal of immunology},
  year={1993},
  volume={151 1},
  pages={277-83}
}
HSV-1 topical infection on the murine cornea can induce herpetic stromal keratitis (HSK), a T cell-mediated inflammatory response that results in blindness. To begin to decipher the molecular interactions involved in this infection, extracts of infected corneas were assayed for the presence of seven different cytokines by ELISA. The most prominent cytokines detected were IL-1 alpha and IL-6. Both were elevated by day 2 after infection, reached peak levels of 82 and 538 pg/cornea, respectively… CONTINUE READING

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