Cytokine expression in dogs with natural Leishmania infantum infection.

@article{Panaro2009CytokineEI,
  title={Cytokine expression in dogs with natural Leishmania infantum infection.},
  author={Maria Antonietta Panaro and Olga Brandonisio and Anna Maria Cianciulli and Pasqua Cavallo and Vita Lacasella and Paola Paradies and Gabriella Testini and Donato de Caprariis and Vincenzo Mitolo and Domenico Otranto},
  journal={Parasitology},
  year={2009},
  volume={136 8},
  pages={823-31}
}
The aim of this study was to evaluate cytokine expression in 22 Leishmania infantum naturally infected dogs, in order to correlate this parameter with the clinical status of infected animals. After 4 and 8 months from the first diagnosis of Leishmania infection, clinical and laboratory examination of dogs was performed and peripheral blood mononuclear cells (PBMC) were isolated. The cytokine profile was analysed in terms of IFN-gamma, IL-4, IL-10 and TNF-alpha mRNA expression in cultured PBMC… CONTINUE READING
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