Cytokine effects on CNS biogenic amines.


The administration of purified cytokines to animals has been shown to cause a number of effects on the brain, including neuroendocrine effects, behavioral effects and alterations of brain biogenic amines. The best-documented effects are the activation by interleukin-1 (IL-1) of the hypothalamo-pituitary-adrenocortical (HPA) axis, and cerebral norepinephrine… (More)


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