Cytokine blockade as a new strategy to treat rheumatoid arthritis: inhibition of tumor necrosis factor.

@article{Fox2000CytokineBA,
  title={Cytokine blockade as a new strategy to treat rheumatoid arthritis: inhibition of tumor necrosis factor.},
  author={David A Fox},
  journal={Archives of internal medicine},
  year={2000},
  volume={160 4},
  pages={437-44}
}
  • David A Fox
  • Published 2000 in Archives of internal medicine
Rheumatoid arthritis (RA) is a common, frequently severe, chronic inflammatory disease. Although the cause of RA remains unknown, recent advances in understanding its pathogenesis have been substantial. Despite the use of a variety of medications, particularly methotrexate, treatment of RA is not fully effective in most patients. Until recently, insights into inflammatory mechanisms in RA had not been successfully translated into novel classes of therapeutic agents. This gap now will likely be… CONTINUE READING