Cytokine and contact-dependent activation of natural killer cells by influenza A or Sendai virus-infected macrophages.

@article{Sirn2004CytokineAC,
  title={Cytokine and contact-dependent activation of natural killer cells by influenza A or Sendai virus-infected macrophages.},
  author={Jukka Sir{\'e}n and Timo Sareneva and Jaana Pirhonen and Mari Strengell and Ville Veckman and Ilkka Julkunen and Sampsa Matikainen},
  journal={The Journal of general virology},
  year={2004},
  volume={85 Pt 8},
  pages={2357-64}
}
NK cells participate in innate immune responses by secreting gamma interferon (IFN-gamma) and by destroying virus-infected cells. Here the interaction between influenza A or Sendai virus-infected macrophages and NK cells has been studied. A rapid, cell-cell contact-dependent production of IFN-gamma from NK cells cultured with virus-infected macrophages was… CONTINUE READING