Cytokine and chemokine regulation of sensory neuron function.

@article{Miller2009CytokineAC,
  title={Cytokine and chemokine regulation of sensory neuron function.},
  author={Richard J. Miller and Hosung Jung and Sonia Kaur Bhangoo and Fletcher A White},
  journal={Handbook of experimental pharmacology},
  year={2009},
  volume={194},
  pages={
          417-49
        }
}
Pain normally subserves a vital role in the survival of the organism, prompting the avoidance of situations associated with tissue damage. However, the sensation of pain can become dissociated from its normal physiological role. In conditions of neuropathic pain, spontaneous or hypersensitive pain behavior occurs in the absence of the appropriate stimuli. Our incomplete understanding of the mechanisms underlying chronic pain hypersensitivity accounts for the general ineffectiveness of currently… CONTINUE READING
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