Cytokine Release, Pancreatic Injury, and Risk of Acute Pancreatitis After Spinal Fusion Surgery

  title={Cytokine Release, Pancreatic Injury, and Risk of Acute Pancreatitis After Spinal Fusion Surgery},
  author={Zhaoping He and Dalal J. F. Tonb and Kirk W. Dabney and Freeman Miller and Suken A. Shah and B. Randall Brenn and Mary C. Theroux and Devendra Indulal Mehta},
  journal={Digestive Diseases and Sciences},
Acute pancreatitis after posterior spinal fusion in children is associated with high intraoperative blood loss. Inflammation, oxidative stress, and pancreatitis markers were assessed during this period. Five of the 17 patients studied developed acute pancreatitis 3–7 days after surgery. Intraoperative blood loss (4850±2315 vs 1322±617 ml) and peak tumor necrosis factor α levels (15.29±5.3 vs 8.27±4.6 pg/ml) in the immediate postoperative period were significantly higher in these five patients… CONTINUE READING


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