Cytokine Levels Correlate with Immune Cell Infiltration after Anti-VEGF Therapy in Preclinical Mouse Models of Breast Cancer

@inproceedings{Roland2009CytokineLC,
  title={Cytokine Levels Correlate with Immune Cell Infiltration after Anti-VEGF Therapy in Preclinical Mouse Models of Breast Cancer},
  author={Christina L Roland and Kristi D. Lynn and Jason E. Toombs and Sean P. Dineen and D Gomika Udugamasooriya and Rolf A Brekken},
  booktitle={PloS one},
  year={2009}
}
The effect of blocking VEGF activity in solid tumors extends beyond inhibition of angiogenesis. However, no studies have compared the effectiveness of mechanistically different anti-VEGF inhibitors with respect to changes in tumor growth and alterations in the tumor microenvironment. In this study we use three distinct breast cancer models, a MDA-MB-231… CONTINUE READING