Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila.

  title={Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila.},
  author={Olivier Lamiable and Christine Kellenberger and Cordula Kemp and Laurent Troxler and Nad{\`e}ge Pelte and Michael Boutros and Jo{\~a}o Trindade Marques and Laurent Daeffler and Jules A. Hoffmann and Alain Roussel and Jean-Luc Imler},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={113 3},
Viruses are obligatory intracellular parasites that suffer strong evolutionary pressure from the host immune system. Rapidly evolving viral genomes can adapt to this pressure by acquiring genes that counteract host defense mechanisms. For example, many vertebrate DNA viruses have hijacked cellular genes encoding cytokines or cytokine receptors to disrupt host cell communication. Insect viruses express suppressors of RNA interference or apoptosis, highlighting the importance of these cell… CONTINUE READING
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