Cytokine‐mediated regulation of activating and inhibitory Fcγ receptors in human monocytes

  title={Cytokine‐mediated regulation of activating and inhibitory Fcγ receptors in human monocytes},
  author={Y. Liu and Emi Masuda and M. Blank and K. Kirou and Xiaoni Gao and M. Park and L. Pricop},
  journal={Journal of Leukocyte Biology},
  • Y. Liu, Emi Masuda, +4 authors L. Pricop
  • Published 2005
  • Biology
  • Journal of Leukocyte Biology
  • Fcγ receptors (FcγR) trigger inflammatory reactions in response to immunoglbulin‐opsonized pathogens and antigen‐antibody complexes. The coordinate expression of activating and inhibitory FcγR ensures the homeostasis of immune complex‐driven inflammatory responses. In this study, we used antibodies with preferential binding for activating FcγRIIa and inhibitory FcγRIIb receptors to investigate the expression and regulation of FcγRII isoforms in human monocytes. Cross‐linking of FcγRIIa… CONTINUE READING
    Cytokine‐regulated expression and inhibitory function of FcγRIIB1 and ‐B2 receptors in human dendritic cells
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