Cytokeratins as serum markers in lung cancer: a comparison of CYFRA 21-1 and TPS.

@article{Pujol1996CytokeratinsAS,
  title={Cytokeratins as serum markers in lung cancer: a comparison of CYFRA 21-1 and TPS.},
  author={Jean-Louis Pujol and Jean Grenier and E Parrat and Matthias Lehmann and Tom Lafontaine and Xavier Quantin and François B. Michel},
  journal={American journal of respiratory and critical care medicine},
  year={1996},
  volume={154 3 Pt 1},
  pages={725-33}
}
We examined two recently described cytokeratin markers, CYFRA 21-1 (cytokeratin fragment recognized by KS 19-1 and BM 19-21 antibodies) and TPS (specific M3 epitope of the tissue polypeptide antigen), in 405 lung cancer patients (91 small-cell and 314 non-small-cell lung cancers) and 59 patients presenting with nonmalignant pulmonary disease. Sensitivity-specificity relationship, as analyzed by receiver operating characteristic curves, demonstrated a higher accuracy of CYFRA 21-1 in comparison… CONTINUE READING

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