Cytokeratin markers come of age.

@article{Linder2007CytokeratinMC,
  title={Cytokeratin markers come of age.},
  author={Stig Linder},
  journal={Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine},
  year={2007},
  volume={28 4},
  pages={189-95}
}
  • Stig Linder
  • Published 2007 in
    Tumour biology : the journal of the International…
Cytokeratins have been extensively used as serum tumour markers for monitoring of disease progression in cancer patients. The source of cytokeratins in the circulation as well as the mechanisms of release from cells have long been unclear. Recent evidence suggests that cytokeratins present in the circulation of cancer patients are released from apoptotic or necrotic tumour cells. CK18 is cleaved by caspases during apoptosis and a monoclonal antibody (M30) specific to caspase-cleaved forms is… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

(Cleaved) CK18 serum and tissue expression levels differentiate acute HCV reinfection from acute rejection in liver allografts.

Liver international : official journal of the International Association for the Study of the Liver • 2015
View 4 Excerpts
Highly Influenced

Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patients.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology • 2009
View 5 Excerpts
Highly Influenced

The human keratins: biology and pathology

Histochemistry and Cell Biology • 2008
View 5 Excerpts
Highly Influenced

Cytokeratin-18 in Diagnosis of HCC in Patients with Liver Cirrhosis

Asian Pacific journal of cancer prevention : APJCP • 2017
View 1 Excerpt

Similar Papers

Loading similar papers…