Cytokeratin 8 and 18 expression in imprint smears of chronic viral hepatitis, autoimmune hepatitis and hepatocellular carcinoma. A preliminary study.

@article{Athanassiadou2007Cytokeratin8A,
  title={Cytokeratin 8 and 18 expression in imprint smears of chronic viral hepatitis, autoimmune hepatitis and hepatocellular carcinoma. A preliminary study.},
  author={Pauline Athanassiadou and Helen Psyhoyiou and Dimitra S Grapsa and Maria Gonidi and Ioannis G Ketikoglou and Efstratios S. Patsouris},
  journal={Acta cytologica},
  year={2007},
  volume={51 1},
  pages={61-5}
}
OBJECTIVE To investigate whether the expression of cytokeratin (CK) 8 and 18 is altered in chronic active viral hepatitis, autoimmune hepatitis and hepatocellular carcinoma. STUDY DESIGN Cytologic imprint smears were obtained from 53 liver core biopsy specimens and were studied immunocytochemically for the expression of CK8 and 18. RESULTS CK8-positive expression was observed in 45.5% of chronic active hepatitis B (CH-B), 20% of chronic active hepatitis C (CH-C), 90% of autoimmune hepatitis… CONTINUE READING