Cytogenetic studies in T-cell acute lymphoblastic leukemia (1981-2002).

  title={Cytogenetic studies in T-cell acute lymphoblastic leukemia (1981-2002).},
  author={Nathalie Douet-Guilbert and Fr{\'e}d{\'e}ric Morel and Marie-Jos{\'e}e Le Bris and Ang{\`e}le Herry and Genevi{\`e}ve Le Calvez and V{\'e}ronique Marion and Jean-francois Abgrall and Christian Berthou and Marc de Braekeleer},
  journal={Leukemia & lymphoma},
  volume={45 2},
Chromosomal analysis was successfully performed in 34 of the 37 patients with T-cell acute lymphoblastic leukemia (ALL) seen at the University Hospital in Brest (France) between 1981 and 2002. A normal karyotype was observed in 29.4% of the patients. Numerical changes were rare, 79.2% of the abnormal karyotypes being pseudodiploid. All 24 abnormal karyotypes had at least a structural rearrangement. Translocations involving band 14q11, that contains the T-cell receptor (TCR) alpha and delta… CONTINUE READING