Cytogenetic profile of 109 lipomas.

  title={Cytogenetic profile of 109 lipomas.},
  author={Chandrika Sreekantaiah and Stanley P. L. Leong and Constantine P. Karakousis and Daniel L Mcgee and W D Rappaport and Hugo V. Villar and David Neal and Susan M. Fleming and A Wankel and P N Herrington},
  journal={Cancer research},
  volume={51 1},
Cytogenetic analysis of short-term cultures was carried out on 109 lipomas from 92 patients. Clonal chromosomal abnormalities were present in 50% of the tumors analyzed. Based on the results, three main cytogenetic groups were identified and included: (a) tumors with normal karyotypes, (b) tumors with abnormalities involving region q13-15 on chromosome 12, and (c) tumors with other clonal aberrations. Within each of these groups, cytogenetic subgroups could be identified, each characterized by… CONTINUE READING