Cytogenetic findings in 33 osteosarcomas.

  title={Cytogenetic findings in 33 osteosarcomas.},
  author={Fredrik Mertens and Nils Mandahl and Charlotte Orndal and Bo Baldetorp and Henrik C. F. Bauer and Anders Rydholm and Thomas Wiebe and Helena Will{\'e}n and M. A. Akerman and Sverre Heim},
  journal={International journal of cancer},
  volume={55 1},
Thirty-three osteosarcomas (OS) were analyzed cytogenetically. Clonal chromosome changes were detected in 17 cases. Six tumors had chromosome numbers in the diploid range, 6 in the triploid range, 1 in the tetraploid range and 1 in the pentaploid range, while 3 tumors had multiple clones with different ploidy levels. Including the present 17 tumors, a total of 27 OS with clonal aberrations have been reported. The recognizable structural rearrangements in these 27 tumors clustered to chromosome… CONTINUE READING


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