Cytogenetic effects on cells derived from patients with myelodysplastic syndromes during treatment with hemopoietic growth factors.

@article{Verhoef1992CytogeneticEO,
  title={Cytogenetic effects on cells derived from patients with myelodysplastic syndromes during treatment with hemopoietic growth factors.},
  author={Gregor E. G. Verhoef and Herman Van den Berghe and M. A. Boogaerts},
  journal={Leukemia},
  year={1992},
  volume={6 8},
  pages={766-9}
}
Hemopoietic growth factors are used with increasing frequency in the treatment of patients with myelodysplastic syndromes (MDS). While a response occurs regularly, it has not been unequivocally resolved whether this effect is due to the stimulation of normal hemopoiesis or to induced maturation of the abnormal clone. To determine whether selective responses to colony-stimulating factors of normal versus abnormal clones occurred, cytogenetic analysis was performed on bone marrow cells of MDS… CONTINUE READING