Cytogenetic damage in human blood lymphocytes exposed in vitro to radon.

  title={Cytogenetic damage in human blood lymphocytes exposed in vitro to radon.},
  author={V Zareena Hamza and Mary N. Mohankumar},
  journal={Mutation research},
  volume={661 1-2},
The effect of radon in inducing DNA damage was investigated in vitro by two well-established cytogenetic assays. Blood samples were irradiated with radon using a novel irradiation assembly. Doses varied between 0 and 127 mGy for chromosome aberration (CA) assay and 0 and 120 mGy for cytokinesis blocked micronucleus (CBMN) assay. Dose-rates varied between 0.000054 and 0.708 mGy/min. After the irradiation period of 3h, excess radon gas was released and cultures were initiated using standard… CONTINUE READING
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