Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors.

Abstract

We analyzed the karyotype of 27 B-cell lymphomas of human origin that developed in mice with severe combined immunodeficiency disease following the injection of peripheral blood leukocytes from Epstein-Barr virus-seropositive donors. Three tumors had clonal abnormalities detected with conventional techniques, 2 had trisomy 11, and 1 had a del(6)(q21q25… (More)

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@article{Thangavelu1992CytogeneticCO, title={Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors.}, author={Maya Thangavelu and L. Snyder and John Anastasi and Michelle M Le Beau and M B Kirven and Gast{\~A}3nR. Picchio and D. Mosier and Jessica Rowley}, journal={Cancer research}, year={1992}, volume={52 17}, pages={4678-81} }