Cytogenetic and morphologic typing of 58 papillary renal cell carcinomas: evidence for a cytogenetic evolution of type 2 from type 1 tumors.

@article{Gunawan2003CytogeneticAM,
  title={Cytogenetic and morphologic typing of 58 papillary renal cell carcinomas: evidence for a cytogenetic evolution of type 2 from type 1 tumors.},
  author={Bastian Gunawan and Anja von Heydebreck and Thekla Fritsch and Wolfgang Huber and R. Ringert and Gerhard Jakse and L{\'a}szl{\'o} F{\"u}zesi},
  journal={Cancer research},
  year={2003},
  volume={63 19},
  pages={6200-5}
}
We evaluated clinical characteristics, patient outcome (mean follow-up, 47 months), and cytogenetic abnormalities in the largest as yet reported cytogenetic series of 47 primary and 11 secondary papillary renal cell carcinomas for differences between the recently proposed type 1 and type 2 subtypes. Secondary tumors were more often of type 2 morphology (P = 0.02), whereas primary type 2 tumors were associated with higher clinical stage (P = 0.001) and worse patient outcome (P = 0.02). Although… CONTINUE READING

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