Cytogenetic analysis of the first cleavage division in mouse embryos (fertilization-pronuclei-T163H translocation).

  • Ryan P Donahue
  • Published 1972 in
    Proceedings of the National Academy of Sciences…


Chromosome counts of 338 mouse zygotes at late prophase and metaphase of the first cleavage division revealed 96.4% diploidy, 1.8% hypodiploidy, 1.2% triploidy, and 0.3% tetraploidy. One additional anomaly might have given rise to an embryo mosaic for maternal but not paternal genes. In zygotes collected without colchicine administration to the mother, one… (More)


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