Cytogenetic analysis of 39 pediatric central nervous system tumors.

  title={Cytogenetic analysis of 39 pediatric central nervous system tumors.},
  author={Pamela S Karnes and Thanh Ngoc Tran and Minggang Cui and Corey Raffel and Floyd Gilles and John A. Barranger and K. L. Ying},
  journal={Cancer genetics and cytogenetics},
  volume={59 1},
Consistent cytogenetic abnormalities have been described in many pediatric solid tumors, including Ewing's sarcoma, Wilms' tumor, and neuroblastoma. Similar analysis of pediatric central nervous system (CNS) tumors has been hampered by technical problems. We report chromosome results from 39 pediatric CNS tumors. Abnormalities of chromosome 17 were noted in 3 of 11 primitive neuroectodermal tumors (including i(17q) in 2 tumors), confirming data observed by other investigators. Cells from 2 of… CONTINUE READING
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