Cytogenetic analyses of human oocytes provide new data on non-disjunction mechanisms and the origin of trisomy 16.

@article{GarciaCruz2010CytogeneticAO,
  title={Cytogenetic analyses of human oocytes provide new data on non-disjunction mechanisms and the origin of trisomy 16.},
  author={Raquel Garcia-Cruz and A. M. Casanovas and Miguel A Brie{\~n}o-Enr{\'i}quez and Pedro Robles and Ignasi Roig and A{\"i}da Pujol and Llu{\'i}s Cabero and Merc{\'e} Durb{\'a}n and Montserrat Garcia Cald{\'e}s},
  journal={Human reproduction},
  year={2010},
  volume={25 1},
  pages={179-91}
}
BACKGROUND Nowadays, oocyte donation is an extended practise in IVF programmes. However, to date, little information on aneuploidy frequency in oocytes from donors is available. Aneuploidy is one of the major causes of embryo and fetal wastage as well as of congenital mental and developmental disabilities. It is known that most aneuploidies are due to non-disjunction events occurring in the maternal germ line. Linkage studies have associated abnormal patterns of meiotic recombination to the… CONTINUE READING
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…