Cytogenetic abnormalities in anin situ ductal carcinoma and five prophylactically removed breasts from members of a family with hereditary breast cancer

Abstract

Short-term cultures of tissue samples from three bilateral prophylactic mastectomies and onein situ ductal carcinoma from four women belonging to a family with hereditary breast cancer were cytogenetically analyzed. Clonal chromosome abnormalities were detected in five of the six prophylactically removed breasts, all of which had the histologic diagnosis… (More)
DOI: 10.1007/BF01806672

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