Cytochrome c-lipid interactions: new insights from resonance energy transfer.

  title={Cytochrome c-lipid interactions: new insights from resonance energy transfer.},
  author={Valeriya M. Trusova and Galyna P. Gorbenko and Julian G. Molotkovsky and Paavo K. J. Kinnunen},
  journal={Biophysical journal},
  volume={99 6},
Resonance energy transfer (RET) from anthrylvinyl-labeled phosphatidylcholine (AV-PC) or cardiolipin (AV-CL) to cytochrome c (cyt c) heme moiety was employed to assess the molecular-level details of protein interactions with lipid bilayers composed of PC with 2.5 (CL2.5), 5 (CL5), 10 (CL10), or 20 (CL20) mol % CL under conditions of varying ionic strength and lipid/protein molar ratio. Monte Carlo analysis of multiple data sets revealed a subtle interplay between 1), exchange of the neutral and… CONTINUE READING


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