Cytochrome bd oxidase from Escherichia coli displays high catalase activity: An additional defense against oxidative stress

@article{Borisov2013CytochromeBO,
  title={Cytochrome bd oxidase from Escherichia coli displays high catalase activity: An additional defense against oxidative stress},
  author={V. Borisov and E. Forte and A. Davletshin and D. Mastronicola and P. Sarti and A. Giuffr{\`e}},
  journal={FEBS Letters},
  year={2013},
  volume={587}
}
  • V. Borisov, E. Forte, +3 authors A. Giuffrè
  • Published 2013
  • Chemistry, Medicine
  • FEBS Letters
  • Cytochrome bd oxygen reductase from Escherichia coli has three hemes, b 558, b 595 and d. We found that the enzyme, as‐prepared or in turnover with O2, rapidly decomposes H2O2 with formation of approximately half a mole of O2 per mole of H2O2. Such catalase activity vanishes upon cytochrome bd reduction, does not compete with the oxygen‐reductase activity, is insensitive to NO, CO, antimycin‐A and N‐ethylmaleimide (NEM), but is inhibited by cyanide (K i ∼2.5 μM) and azide. The activity… CONTINUE READING
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    References

    SHOWING 1-10 OF 41 REFERENCES
    Two sources of endogenous hydrogen peroxide in Escherichia coli
    • 116
    • Highly Influential
    Redox control of fast ligand dissociation from Escherichia coli cytochrome bd.
    • 51
    Cytochrome bd oxidase and nitric oxide: From reaction mechanisms to bacterial physiology
    • 52
    Roles of respiratory oxidases in protecting Escherichia coli K12 from oxidative stress
    • 80
    The cytochrome bd respiratory oxygen reductases.
    • 293
    Cytochrome bd confers nitric oxide resistance to Escherichia coli.
    • 126
    Peroxidase activity of cytochrome bd from Escherichia coli
    • 21