Cytochrome b5 reductase and the control of lipid metabolism and healthspan


Cytochrome b5 reductases (CYB5R) are required for the elongation and desaturation of fatty acids, cholesterol synthesis and mono-oxygenation of cytochrome P450 enzymes, all of which are associated with protection against metabolic disorders. However, the physiological role of CYB5R in the context of metabolism, healthspan and aging remains ill-defined. We… (More)
DOI: 10.1038/npjamd.2016.6


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