Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.

@article{Hardwick2008CytochromePO,
  title={Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases.},
  author={James P. Hardwick},
  journal={Biochemical pharmacology},
  year={2008},
  volume={75 12},
  pages={
          2263-75
        }
}
The cytochrome P450 gene 4 family (CYP4) consists of a group of over 63 members that omega-hydroxylate the terminal carbon of fatty acids. In mammals, six subfamilies have been identified and three of these subfamily members show a preference in the metabolism of short (C7-C10)-CYP4B, medium (C10-C16)-CYP4A, and long (C16-C26)-CYP4F, saturated, unsaturated and branched chain fatty acids. These omega-hydroxylated fatty acids are converted to dicarboxylic acids, which are preferentially… CONTINUE READING
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