Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain.

@article{Pittendrigh1997CytochromePG,
  title={Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain.},
  author={B. Pittendrigh and K. Aronstein and E. Zinkovsky and O. Andreev and B. Campbell and J. Daly and S. Trowell and R. Ffrenchconstant},
  journal={Insect biochemistry and molecular biology},
  year={1997},
  volume={27 6},
  pages={
          507-12
        }
}
  • B. Pittendrigh, K. Aronstein, +5 authors R. Ffrenchconstant
  • Published 1997
  • Biology, Medicine
  • Insect biochemistry and molecular biology
  • The molecular basis of metabolic resistance to pyrethroids in Helicoverpa armigera is currently under debate. Substantial indirect evidence supports a role for both esterase- and cytochrome-P450-mediated metabolism. However, the relative roles played by these two mechanisms in field-based resistance is uncertain. Our understanding of the importance of P450-mediated metabolism is hindered by the paucity of cloned genes from this species, and the corresponding absence of data on rates of… CONTINUE READING
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