Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain.
@article{Pittendrigh1997CytochromePG, title={Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain.}, author={B. Pittendrigh and K. Aronstein and E. Zinkovsky and O. Andreev and B. Campbell and J. Daly and S. Trowell and R. Ffrenchconstant}, journal={Insect biochemistry and molecular biology}, year={1997}, volume={27 6}, pages={ 507-12 } }
The molecular basis of metabolic resistance to pyrethroids in Helicoverpa armigera is currently under debate. Substantial indirect evidence supports a role for both esterase- and cytochrome-P450-mediated metabolism. However, the relative roles played by these two mechanisms in field-based resistance is uncertain. Our understanding of the importance of P450-mediated metabolism is hindered by the paucity of cloned genes from this species, and the corresponding absence of data on rates of… CONTINUE READING
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