Cytochrome P450 gene polymorphism and cancer.


Human cytochrome P450 (CYP) enzymes play a key role in the metabolism of drugs and environmental chemicals. Several CYP enzymes metabolically activate procarcinogens to genotoxic intermediates. Phenotyping analyses revealed an association between CYP enzyme activity and the risk to develop several forms of cancer. Research carried out in the last decade… (More)


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@article{Agndez2004CytochromePG, title={Cytochrome P450 gene polymorphism and cancer.}, author={Jos{\'e} A G Ag{\'u}ndez}, journal={Current drug metabolism}, year={2004}, volume={5 3}, pages={211-24} }