Cytochrome P450 2E1 gene polymorphism and alcohol drinking on the risk of hepatocellular carcinoma: a meta-analysis

@article{Liu2014CytochromeP2,
  title={Cytochrome P450 2E1 gene polymorphism and alcohol drinking on the risk of hepatocellular carcinoma: a meta-analysis},
  author={Wei Liu and Fang Tian and Li-ping Dai and Yurong Chai},
  journal={Molecular Biology Reports},
  year={2014},
  volume={41},
  pages={7645-7650}
}
The gene polymorphism of Cytochrome P450 2E1 (CYP2E1) is supposed to be associated with cancer susceptibility. Many studies focusing on the Pst I/Rsa I polymorphism of CYP2E1 gene and hepatocellular carcinoma (HCC) risk have been conducted and the results are conflicting. In the current study, a meta-analysis of published studies was performed to assess the association between CYP2E1 Pst I/Rsa I polymorphism and risk to HCC. 11 studies containing 1,178 cases and 1,623 controls were selected to… CONTINUE READING
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