Cytochalasin inhibits the rate of elongation of actin filament fragments

@article{Brown1979CytochalasinIT,
  title={Cytochalasin inhibits the rate of elongation of actin filament fragments},
  author={S Y Brown and J Spudich},
  journal={The Journal of Cell Biology},
  year={1979},
  volume={83},
  pages={657 - 662}
}
Submicromolar concentrations of cytochalasin inhibit the rate of assembly of highly purified dictyostelium discoideum actin, using a cytochalasin concentration range in which the final extent of assembly is minimally affected. Cytochalasin D is a more effective inhibitor than cytochalasin B, which is in keeping with the effects that have been reported on cell motility and with binding to a class of high-affinity binding sites from human erythrocyte membranes (Lin and Lin. 1978. J. Biol. CHem… CONTINUE READING
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