Cytochalasin D induces changes in cell shape and promotes in vitro chondrogenesis: a morphological study.

@article{Loty1995CytochalasinDI,
  title={Cytochalasin D induces changes in cell shape and promotes in vitro chondrogenesis: a morphological study.},
  author={Sabine Loty and Nadine Forest and Habib Boulekbache and Jean Michel Sautier},
  journal={Biology of the cell},
  year={1995},
  volume={83 2-3},
  pages={149-61}
}
One of the initial events required for the expression of cartilage-specific macromolecules in monolayer cultures is the reversion to the initial round shape of chondrocytes. Thus, considerable research efforts have focused on developing reliable procedures to maintain a round morphology of cultured chondrocytes. Our study focuses on evaluating the response of dedifferentiated fetal rat chondrocytes to cytochalasin D, an actin-disrupting agent, with special emphasis on the morphological events… CONTINUE READING

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