Cyto-Sim: a formal language model and stochastic simulator of membrane-enclosed biochemical processes

@article{Sedwards2007CytoSimAF,
  title={Cyto-Sim: a formal language model and stochastic simulator of membrane-enclosed biochemical processes},
  author={Sean Sedwards and Tommaso Mazza},
  journal={Bioinformatics},
  year={2007},
  volume={23 20},
  pages={2800-2}
}
MOTIVATION Compartments and membranes are the basis of cell topology and more than 30% of the human genome codes for membrane proteins. While it is possible to represent compartments and membrane proteins in a nominal way with many mathematical formalisms used in systems biology, few, if any, explicitly model the topology of the membranes themselves. Discrete stochastic simulation potentially offers the most accurate representation of cell dynamics. Since the details of every molecular… CONTINUE READING
Highly Cited
This paper has 32 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Bio-inspired Computing – Theories and Applications

Communications in Computer and Information Science • 2016

Compartmental rule-based modeling of biochemical systems

Proceedings of the 2009 Winter Simulation Conference (WSC) • 2009
View 2 Excerpts

Similar Papers

Loading similar papers…