Cystine knot growth factors and their functionally versatile proregions.

@article{Schwarz2017CystineKG,
  title={Cystine knot growth factors and their functionally versatile proregions.},
  author={Elisabeth Schwarz},
  journal={Biological chemistry},
  year={2017},
  volume={398 12},
  pages={
          1295-1308
        }
}
The cystine knot disulfide pattern has been found to be widespread in nature, since it has been detected in proteins from plants, marine snails, spiders and mammals. Cystine knot proteins are secreted proteins. Their functions range from defense mechanisms as toxins, e.g. ion channel or enzyme inhibitors, to hormones, blood factors and growth factors. Cystine knot proteins can be divided into two superordinate groups. (i) The cystine knot peptides, also referred to - with other non-cystine knot… CONTINUE READING

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