Cystine/glutamate exchange serves as the source for extracellular glutamate: Modifications by repeated cocaine administration

@article{Baker2002CystineglutamateES,
  title={Cystine/glutamate exchange serves as the source for extracellular glutamate: Modifications by repeated cocaine administration},
  author={David A. Baker and Hui Shen and Peter W. Kalivas},
  journal={Amino Acids},
  year={2002},
  volume={23},
  pages={161-162}
}
 Repeated administration of cocaine lowers the basal extracellular levels of glutamate in the nucleus accumbens as measured by microdialysis. The studies presented reveal that this long-term neuroadaptation elicited by repeated cocaine results from a decrease in the activity of cystine/glutamate exchange. 

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