Cystic fibrosis
@article{Osullivan2009CysticF, title={Cystic fibrosis}, author={B. O'sullivan and S. Freedman}, journal={The Lancet}, year={2009}, volume={373}, pages={1891-1904} }
Cystic fibrosis is the most common lethal genetic disease in white populations. The outlook for patients with the disease has improved steadily over many years, largely as a result of earlier diagnosis, more aggressive therapy, and provision of care in specialised centres. Researchers now have a more complete understanding of the molecular-biological defect that underlies cystic fibrosis, which is leading to new approaches to treatment. One of these treatments, hypertonic saline, is already in… CONTINUE READING
Topics from this paper
Paper Mentions
Observational Clinical Trial
Cystic fibrosis (CF) is the most common lethal inherited disease in Caucasian populations. To
improve survival, it is essential to understand the development, progression and treatment… Expand
Conditions | Cystic Fibrosis, Healthy |
---|---|
Intervention | Diagnostic Test |
Observational Clinical Trial
The investigators aim to assess whether pulmonary MRI (hyperpolarised 129Xe ventilation
imaging [Xe-MRI]) can detect changes in ventilation defects in patients with CF before and… Expand
Conditions | Cystic Fibrosis |
---|
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