Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Allelic Variants Relate to Shifts in Faecal Microbiota of Cystic Fibrosis Patients

Abstract

INTRODUCTION In this study we investigated the effects of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene variants on the composition of faecal microbiota, in patients affected by Cystic Fibrosis (CF). CFTR mutations (F508del is the most common) lead to a decreased secretion of chloride/water, and to mucus sticky secretions, in pancreas… (More)
DOI: 10.1371/journal.pone.0061176

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@inproceedings{Schippa2013CysticFT, title={Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Allelic Variants Relate to Shifts in Faecal Microbiota of Cystic Fibrosis Patients}, author={Serena Schippa and Valerio Iebba and Floriana Santangelo and Antonella Gagliardi and Riccardo Valerio De Biase and Antonella Stamato and Serenella Bertasi and Marco Lucarelli and Maria P Conte and Serena Quattrucci}, booktitle={PloS one}, year={2013} }