Cystic Fibrosis: Cystic fibrosis and lactase persistence: a possible correlation

@article{Modiano2007CysticFC,
  title={Cystic Fibrosis: Cystic fibrosis and lactase persistence: a possible correlation},
  author={G. Modiano and B. Ciminelli and P. Pignatti},
  journal={European Journal of Human Genetics},
  year={2007},
  volume={15},
  pages={255-259}
}
  • G. Modiano, B. Ciminelli, P. Pignatti
  • Published 2007
  • Biology, Medicine
  • European Journal of Human Genetics
  • C ystic fibrosis (CF) is the most common lethal genetic disease in Europeans and is transmitted as an autosomal recessive disorder caused by loss of function of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. Since long it has been supposed that its quite high frequency (1/ 2500 implying an allele frequency equal to 0.02) is due to a Europe-restricted selective advantage of the heterozygous CF/þ individuals. Nevertheless, this hypothesis has never been directly demonstrated… CONTINUE READING
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