Cysteine supplementation improves the erythrocyte glutathione synthesis rate in children with severe edematous malnutrition.

@article{Badaloo2002CysteineSI,
  title={Cysteine supplementation improves the erythrocyte glutathione synthesis rate in children with severe edematous malnutrition.},
  author={A. Badaloo and M. Reid and T. Forrester and W. Heird and F. Jahoor},
  journal={The American journal of clinical nutrition},
  year={2002},
  volume={76 3},
  pages={
          646-52
        }
}
  • A. Badaloo, M. Reid, +2 authors F. Jahoor
  • Published 2002
  • Medicine
  • The American journal of clinical nutrition
  • BACKGROUND Children with severe edematous malnutrition have higher than normal oxidant damage and lower concentrations of the antioxidant reduced glutathione (GSH), which are associated with slower synthesis of GSH and with low extra- and intracellular concentrations of the precursor amino acid cysteine. OBJECTIVE We tested whether early dietary supplementation with cysteine could restore a normal GSH concentration and synthesis rate in these children. DESIGN Erythrocyte cysteine and GSH… CONTINUE READING

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    INTERVENTIONAL CLINICAL TRIAL
    Critically ill babies less than 1 month of age have deficient amounts of the antioxidant glutathione and a high incidence of disease associated with oxidative injury compared to… Expand
    ConditionsBronchopulmonary Dysplasia, Necrotizing Enterocolitis, Retinopathy of Prematurity, (+2 more)
    InterventionDietary Supplement

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