Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosis

@inproceedings{Bashir2014CysteineRS,
  title={Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosis},
  author={Samir Al Bashir and Mohammed Alshalalfa and Samar A T Hegazy and Michael Dolph and Bryan Donnelly and Tarek A. Bismar},
  booktitle={Journal of hematology & oncology},
  year={2014}
}
Cysteine- rich secretory protein 3 (CRISP3) prognostic significance in prostate cancer (PCA) has generated mixed result. Herein, we investigated and independently validated CRISP3 expression in relation to ERG and PTEN genomic aberrations and clinical outcome. CRISP3 protein expression was examined by immunohistochemistry using a cohort of patients with localized PCA (n = 215) and castration resistant PCA (CRPC) (n = 46). The Memorial Sloan Kettering (MSKCC) and Swedish cohorts were used for… CONTINUE READING
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ERG expression in prostate cancer: biological relevance and clinical implication

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