Cysteine S-Glutathionylation Promotes Stability and Activation of the Hippo Downstream Effector Transcriptional Co-activator with PDZ-binding Motif (TAZ).

@article{Gandhirajan2016CysteineSP,
  title={Cysteine S-Glutathionylation Promotes Stability and Activation of the Hippo Downstream Effector Transcriptional Co-activator with PDZ-binding Motif (TAZ).},
  author={Rajesh Kumar Gandhirajan and Manaswita Jain and Benedikt Walla and Marc Johnsen and Malte P. Bartram and Minh Huynh Anh and Markus M Rinschen and Thomas Benzing and Bernhard Schermer},
  journal={The Journal of biological chemistry},
  year={2016},
  volume={291 22},
  pages={11596-607}
}
Transcriptional co-activator with PDZ-binding motif (TAZ) and Yes-associated protein (YAP) are critical transcriptional co-activators downstream of the Hippo pathway involved in the regulation of organ size, tissue regeneration, proliferation, and apoptosis. Recent studies suggested common and distinct functions of TAZ and YAP and their diverse impact under… CONTINUE READING