Cysteine Residues Impact the Stability and Micelle Interaction Dynamics of the Human Mitochondrial β-Barrel Anion Channel hVDAC-2

@inproceedings{Maurya2014CysteineRI,
  title={Cysteine Residues Impact the Stability and Micelle Interaction Dynamics of the Human Mitochondrial β-Barrel Anion Channel hVDAC-2},
  author={Svetlana Rajkumar Maurya and Radhakrishnan Mahalakshmi},
  booktitle={PloS one},
  year={2014}
}
The anti-apoptotic 19-stranded transmembrane human voltage dependent anion channel isoform 2 (hVDAC-2) β-barrel stability is crucial for anion transport in mitochondria. The role of the unusually high number of cysteine residues in this isoform is poorly understood. Using a Cys-less construct of hVDAC-2, we have investigated the contribution of cysteines to… CONTINUE READING