Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins.

@article{Ni1997CystatinEI,
  title={Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins.},
  author={Jian Ni and Magnus Abrahamson and Mingjie Zhang and Maria Angustias Fernandez and Anders Grubb and J Su and Geliang L Yu and Yong Li and David Parmelee and Li Zhao Xing and Timothy A. Coleman and Solange Gentz and Rao Thotakura and Nang Nguyen and Mark Hesselberg and Reiner Gentz},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 16},
  pages={10853-8}
}
A new member of the human cystatin superfamily, called cystatin E, has been found by expressed sequence tag (EST) sequencing in amniotic cell and fetal skin epithelial cell cDNA libraries. The sequence of a full-length amniotic cell cDNA clone contained an open reading frame encoding a putative 28-residue signal peptide and a mature protein of 121 amino acids, including four cysteine residues and motifs of importance for the inhibitory activity of Family 2 cystatins like cystatin C. Recombinant… CONTINUE READING

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