Cystatin C: efficacy as screening test for reduced glomerular filtration rate.

  title={Cystatin C: efficacy as screening test for reduced glomerular filtration rate.},
  author={Stefan Herget-Rosenthal and S Trabold and Frank Pietruck and Marianne Holtmann and Th Philipp and Andreas Kribben},
  journal={American journal of nephrology},
  volume={20 2},
Serum cystatin C, a cysteine proteinase inhibitor, has been proposed as a marker of glomerular filtration rate (GFR). Serum cystatin C, serum creatinine and creatinine clearance were measured in 226 patients with various nephropathies, covering the entire range of renal function, to evaluate the efficacy of cystatin C as a screening test to detect reduced creatinine clearance in comparison to creatinine. Subgroups of 53 patients with glomerular and 26 patients with tubular impairment were… CONTINUE READING


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