Cystamine ameliorates liver fibrosis induced by carbon tetrachloride via inhibition of tissue transglutaminase.

@article{Qiu2007CystamineAL,
  title={Cystamine ameliorates liver fibrosis induced by carbon tetrachloride via inhibition of tissue transglutaminase.},
  author={Jiang-feng Qiu and Zhi-qi Zhang and Wei Chen and Zhi-Yong Wu},
  journal={World journal of gastroenterology},
  year={2007},
  volume={13 32},
  pages={4328-32}
}
AIM To investigate the anti-fibrosis effect of the tissue transglutaminase (tTG) specific inhibitor cystamine on liver fibrosis. METHODS Sixty-eight male Sprague Dawley rats were divided into three groups: normal control, liver fibrosis control and cystamine-treated group. Liver fibrosis was induced by intraperitoneal injection of carbon tetrachloride (CCl(4)), and Cystamine was administrated by intraperitoneal injection starting 2 d before the first administration of CCl(4). Animals in each… CONTINUE READING
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