Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem?

@article{Ambrogelly2004CystRNACysFA,
  title={Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem?},
  author={Alexandre Ambrogelly and Satwik Kamtekar and Anselm Sauerwald and Benfang Ruan and Debra Tumbula-Hansen and Dexter Kennedy and Ivan Ahel and Dieter S{\"o}ll},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2004},
  volume={61},
  pages={2437-2445}
}
Aminoacyl-tRNA (transfer RNA) synthetases are essential components of the cellular translation machinery as they provide the ribosome with aminoacyl-tRNAs. Aminoacyl-tRNA synthesis is generally well understood. However, the mechanism of Cys-tRNACys formation in three methanogenic archaea (Methanocaldococcus jannaschii, Methanothermobacter thermautotrophicus… CONTINUE READING